The research in our lab is focused on drug discovery/development for CNS disorders.

Three major directions are being undertaken to development effective small molecules as disease-modifying agents and chemical probes:

  1. Bivalent compounds for Alzheimer's disease;
  2. Curcumin/melatonin hybrids as neuroprotectants for Alzheimer's disease;
  3. Novel NLRP3 inflammasome inhibitors for inflammatory disorders including Alzheimer's disease, multiple sclerosis, traumatic brain injury, and acute myocardial infarction.