Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer's disease.
Bioorg Med Chem, 2015, 23, 7324-31
Curcumin/melatonin hybrid, 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide, ameliorates AD-like pathology in the APP/PS1 mouse model
ACS Chem Neurosci, 2015, 6, 1393-9.
Bivalent compound 17MN exerts neuroprotection through interaction at multiple sites in a cellular model of Alzheimer's disease.
J Alzheimers Dis, 2015, 47, 1021-33.
Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and non-ischemic cardiac injury in the mouse
J Cardiovasc Pharmacol, 2015, 66, 1-8.